tyrosine kinase inhibitor

1. Mechanism of drug resistance for chronic myeloid leukemia to BCR-ABL tyrosine kinase inhibitor
   慢性粒细胞白血病对BCR-ABL酪氨酸激酶靶向抑制剂的耐药机制
2. Erlotinib is a small molecule tyrosine kinase inhibitor that efficiently blocks EGFR.
   厄洛替尼是一种小分子的酪氨酸激酶抑制剂，它能有效地阻断EGFR的作用。
3. This is the first, and, to date, only trial of an epidermal growth factor receptor ( EGFR) tyrosine kinase inhibitor to show a survival advantage for patients with advanced non-small cell lung cancer.
   这是第一次，也是迄今为止惟一的表皮生长因子受体酪氨酸激酶抑制剂的药物临床试验，它能够显示晚期非小细胞肺癌患者经过该药治疗能获得更长生存期。
4. EGFR tyrosine kinase inhibitor is an investigative hot spot in targeted therapy of non-small cell lung cancer ( NSCLC).
   EGFR靶向抑制剂，是目前NSCLC靶向治疗的研究热点之一。
5. The progress in tyrosine kinase inhibitor has been reviewed, including the chemical structures and the pharmacophore models.
   本文综述了近年来酪氨酸激酶抑制剂的研究进展，包括抑制剂的结构和与激酶作用的药效团模型。
6. Design and Synthesis of Novel Pyrrolo [ 2,1-f] [ 1,2,4] triazines as Tyrosine Kinase Inhibitor
   新型吡咯并[2,1-f][1,2,4]三嗪酪氨酸激酶抑制剂的设计与合成
7. Effect of tyrosine kinase inhibitor Imatinib mesylate on proliferation, differentiation and apoptosis of Kasumi-1 leukemia cell line
   伊马替尼体外诱导Kasumi-1细胞增殖、分化与凋亡作用
8. Objective: To discover HER2/ neu tyrosine kinase inhibitor through computer-aided drug design approach.
   目的：用计算机辅助设计法寻找HER2/neu受体酪氨酸激酶小分子抑制剂。
9. And highly selective EGFR tyrosine kinase inhibitor is of potential to be developed into drugs for the treatment of kidney neoplasms.
   选择性EGFR阻断剂是有效的肾肿瘤抑制剂，具有进一步研究和开发的价值。
10. The protein tyrosine kinase inhibitor may be developed as a new kind of effective kidney neoplasm inhibitor.
    酪氨酸激酶抑制剂有望开发成为有效的抗恶性肾肿瘤的药物。
11. Gefitinib ( Iressa, ZD1839) is a selective EGFR-TK ( epidermal growth factor recep-tor tyrosine kinase) inhibitor.
    吉非替尼（gefitinib，Iressa，zD1839）是一种口服选择陛表皮生长因子受体酪氨酸激酶抑制剂。
12. Project Epidermal Growth Factor Receptor Tyrosine Protein Kinase Inhibitor Screen Model
    表皮生长因子受体酪氨酸蛋白激酶抑制剂筛选模型建立
13. Effects of Dexamethasone and protein tyrosine kinase inhibitor on tumour necrosis factor alpha and interleukin 1 beta induced IL-8 production from gastric epithelial cell
    地塞米松及酪氨酸蛋白激酶抑制剂对胃上皮细胞白介素-8分泌抑制作用的实验研究
14. Therapeutic effect of platelet-derived growth factor α and β receptor tyrosine kinase inhibitor on rabbit proliferative vitreoretinopathy
    血小板源性生长因子α和β受体酪氨酸激酶抑制剂对兔PVR的治疗作用
15. The effect of protein tyrosine kinase inhibitor on inflammatory factors induced nitric oxide production in synovial cells
    蛋白酪氨酸激酶抑制剂对炎性因子诱导滑膜细胞产生一氧化氮的影响
16. Effect of Tyrosine Kinase Inhibitor on E-cadherin Expression in Airway Epithelial Cells
    酪氨酸激酶抑制剂对气道上皮细胞上皮钙粘附素表达的影响
17. AIM To study the influence of tyrosine kinase inhibitor, genistein, on the proliferation, DNA synthesis and cell cycle of cultured human keratinocytes.
    目的观察酪氨酸蛋白激酶抑制剂genistein对体外培养的正常人角质形成细胞增殖代谢的影响。
18. The main mechanism is that Genistein is a tyrosine protein kinase inhibitor.
    其抗肿瘤的作用机制主要为通过抑制酪氨酸蛋白激酶的活性，而抑制细胞的生长。
19. Effect of protein tyrosine kinase inhibitor genistein on the kidney carcinoma cell line GRC-1
    金雀异黄素对肾癌细胞系GRC-1细胞生物学行为的影响
20. Objective To investigate the growth inhibiting effect of genistein, a tyrosine protein kinase inhibitor, on the human salivary adenoid cystic carcinoma SACC-83 cell line in vitro, and its effects on the expression of cyclin B1 protein and the cell cycle.
    目的研究酪氨酸蛋白激酶抑制剂genistein抑制人涎腺腺样囊性癌（SACC-83）细胞生长与Cyclinb1蛋白表达和细胞增殖周期的关系。
21. Change in gap junctional intercellular communication in cultured human endothelial cells with hypoxia/ reoxygenation and effect of tyrosine kinase inhibitor on its change
    酪氨酸蛋白激酶抑制剂对缺氧复氧时内皮细胞连接通讯功能的影响
22. Protein Tyrosine Kinase Inhibitor s: Progress and Evaluation
    酪氨酸激酶抑制剂的进展与评价
23. Objective To explore the effect of Genistein, a tyrosine protein kinase inhibitor, on inhibiting the activation of hepatic stellate cells ( HSC).
    目的探索酪氨酸蛋白激酶抑制剂Genistein对肝脏星状细胞（HSC）激活的抑制作用。
24. The inhibitory effect of VEGF on IK was abolished by genistein, a specific tyrosine kinase inhibitor, which suggested that this effect might be related to the stimulation of the activity of this kinase.
    VEGF对IK的抑制作用可以被受体酪氨酸激酶的抑制剂所取消，提示VEGF抑制IK的作用可能与激活该酶活性有关。
25. Tyrosine kinase inhibitors and mitosis inhibitors are powerful anticancer drugs. Research and development of tyrosine kinase inhibitor and mitosis inhibitors have become a hotpot in the research area of anti-anticancer drugs.
    小分子酪氨酸激酶抑制剂和有丝分裂抑制剂均为有效的抗肿瘤药物，对激酶抑制剂和有丝分裂抑制剂的研究与开发已成抗肿瘤药物研究的热点领域。
26. TN-101 is a selective tyrosine kinase inhibitor, with vascular endothelial cell growth factor receptor ( VEGFR) and fibroblast growth factor receptor ( FGFR) as target spots. Pre-clinical study shows TN-101 can effectively inhibit tumor angiogenesis.
    TN-101是以血管细胞内皮生长因子受体（VEGFR）和成纤维细胞生长因子受体（FGFR）为靶点的选择性酪氨酸激酶抑制剂，临床前实验表明它能有效地抑制肿瘤血管生成。

noun

1. a drug used in cases of chronic myeloid leukemia